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In vitro biomimetic engineering of a human hematopoietic niche with functional properties

In adults, human hematopoietic stem and progenitor cells (HSPCs) reside in the bone marrow (BM) microenvironment. Our understanding of human hematopoiesis and the associated niche biology remains limited, due to human material accessibility and limits of existing in vitro culture models. The establi...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Bourgine, Paul E., Klein, Thibaut, Paczulla, Anna M., Shimizu, Takafumi, Kunz, Leo, Kokkaliaris, Konstantinos D., Coutu, Daniel L., Lengerke, Claudia, Skoda, Radek, Schroeder, Timm, Martin, Ivan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016789/
https://ncbi.nlm.nih.gov/pubmed/29866839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1805440115
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