ARL11 regulates lipopolysaccharide-stimulated macrophage activation by promoting mitogen-activated protein kinase (MAPK) signaling

ADP-ribosylation factor-like GTPase 11 (ARL11) is a cancer-predisposing gene that has remained functionally uncharacterized to date. In this study, we report that ARL11 is endogenously expressed in mouse and human macrophages and regulates their activation in response to lipopolysaccharide (LPS) sti...

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Udgivet i:J Biol Chem
Main Authors: Arya, Subhash B., Kumar, Gaurav, Kaur, Harmeet, Kaur, Amandeep, Tuli, Amit
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2018
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016484/
https://ncbi.nlm.nih.gov/pubmed/29618517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000727
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