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The Salmonella effectors SseF and SseG inhibit Rab1A-mediated autophagy to facilitate intracellular bacterial survival and replication

In mammalian cells, autophagy plays crucial roles in restricting further spread of invading bacterial pathogens. Previous studies have established that the Salmonella virulence factors SseF and SseG are required for intracellular bacterial survival and replication. However, the underlying mechanism...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Feng, Zhao-Zhong, Jiang, An-Jie, Mao, An-Wen, Feng, Yuhan, Wang, Weinan, Li, Jingjing, Zhang, Xiaoyan, Xing, Ke, Peng, Xue
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016468/
https://ncbi.nlm.nih.gov/pubmed/29610274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.811737
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