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The Salmonella effectors SseF and SseG inhibit Rab1A-mediated autophagy to facilitate intracellular bacterial survival and replication

In mammalian cells, autophagy plays crucial roles in restricting further spread of invading bacterial pathogens. Previous studies have established that the Salmonella virulence factors SseF and SseG are required for intracellular bacterial survival and replication. However, the underlying mechanism...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Feng, Zhao-Zhong, Jiang, An-Jie, Mao, An-Wen, Feng, Yuhan, Wang, Weinan, Li, Jingjing, Zhang, Xiaoyan, Xing, Ke, Peng, Xue
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016468/
https://ncbi.nlm.nih.gov/pubmed/29610274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.811737
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