The Salmonella effectors SseF and SseG inhibit Rab1A-mediated autophagy to facilitate intracellular bacterial survival and replication

In mammalian cells, autophagy plays crucial roles in restricting further spread of invading bacterial pathogens. Previous studies have established that the Salmonella virulence factors SseF and SseG are required for intracellular bacterial survival and replication. However, the underlying mechanism...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Feng, Zhao-Zhong, Jiang, An-Jie, Mao, An-Wen, Feng, Yuhan, Wang, Weinan, Li, Jingjing, Zhang, Xiaoyan, Xing, Ke, Peng, Xue
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2018
Schlagworte:
Cell Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016468/
https://ncbi.nlm.nih.gov/pubmed/29610274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.811737
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