Isosteric substitution in cationic-amphiphilic polymers reveals an important role for hydrogen bonding in bacterial membrane interactions

Biomimetic antibacterial polymers, the functional mimics of antimicrobial peptides (AMPs), targeting the bacterial cell membrane have been developed to combat the problem of antibiotic resistance. Amphiphilicity, a balance of cationic charge and hydrophobicity, in these polymers has been shown to be...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Uppu, D. S. S. M., Konai, M. M., Baul, U., Singh, P., Siersma, T. K., Samaddar, S., Vemparala, S., Hamoen, L. W., Narayana, C., Haldar, J.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2016
Assuntos:
Chemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016443/
https://ncbi.nlm.nih.gov/pubmed/30155109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc00615a
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