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Why Is a High Temperature Needed by Thermus thermophilus Argonaute During mRNA Silencing: A Theoretical Study

Thermus thermophiles Argonaute (TtAgo) is a complex, which is consisted of 5′-phosphorylated guide DNA and a series of target DNA with catalytic activities at high temperatures. To understand why high temperatures are needed for the catalytic activities, three molecular dynamics simulations and bind...

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Detalhes bibliográficos
Publicado no:Front Chem
Main Authors: Liu, Ye, Yu, Zhengfei, Zhu, Jingxuan, Wang, Song, Xu, Dong, Han, Weiwei
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016274/
https://ncbi.nlm.nih.gov/pubmed/29967763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2018.00223
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