Zoledronic acid exacerbates inflammation through M1 macrophage polarization

BACKGROUND: Zoledronic acid (Zol), one of the bisphosphonates, is frequently utilized for the treatment of osteoporosis and bone metastasis. However, the onset of medication-related osteonecrosis of the jaw (MRONJ) following dental treatments has become a serious issue. We reported previously that o...

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Bibliographische Detailangaben
Veröffentlicht in:Inflamm Regen
Hauptverfasser: Kaneko, Junya, Okinaga, Toshinori, Hikiji, Hisako, Ariyoshi, Wataru, Yoshiga, Daigo, Habu, Manabu, Tominaga, Kazuhiro, Nishihara, Tatsuji
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6015454/
https://ncbi.nlm.nih.gov/pubmed/29977413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41232-018-0074-9
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