IL‐23R Deficiency Does Not Impact Atherosclerotic Plaque Development in Mice

BACKGROUND: Interleukin‐23 (IL‐23) has been implicated in inflammatory and autoimmune diseases by skewing CD4(+) T helper cells towards a pathogenic Th17 phenotype. In this study we investigated the presence of IL‐23 receptor (IL‐23R)‐expressing cells in the atherosclerotic aorta and evaluated the e...

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Dettagli Bibliografici
Pubblicato in:J Am Heart Assoc
Autori principali: Engelbertsen, Daniel, Depuydt, Marie A. C., Verwilligen, Robin A. F., Rattik, Sara, Levinsohn, Erik, Edsfeldt, Andreas, Kuperwaser, Felicia, Jarolim, Petr, Lichtman, Andrew H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6015431/
https://ncbi.nlm.nih.gov/pubmed/29618473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.117.008257
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