Blockade of Tim-1 and Tim-4 Enhances Atherosclerosis in LDL Receptor-Deficient Mice

OBJECTIVE: T cell immunoglobulin and mucin domain (Tim) proteins are expressed by numerous immune cells, recognize phosphatidylserine (PS) on apoptotic cells and function as costimulators or coinhibitors. Tim-1 is expressed by activated T cells but is also found on dendritic cells and B cells. Tim-4...

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Bibliographic Details
Published in:Arterioscler Thromb Vasc Biol
Main Authors: Foks, Amanda C., Engelbertsen, Daniel, Kuperwaser, Felicia, Alberts-Grill, Noah, Gonen, Ayelet, Witztum, Joseph L., Lederer, James, Jarolim, Petr, DeKruyff, Rosemarie H., Freeman, Gordon J., Lichtman, Andrew H.
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4853762/
https://ncbi.nlm.nih.gov/pubmed/26821944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.306860
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