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Xanthine Oxidase Inhibitor Allopurinol Prevents Oxidative Stress‐Mediated Atrial Remodeling in Alloxan‐Induced Diabetes Mellitus Rabbits

BACKGROUND: There are several mechanisms, including inflammation, oxidative stress and abnormal calcium homeostasis, involved in the pathogenesis of atrial fibrillation. In diabetes mellitus (DM), increased oxidative stress may be attributable to higher xanthine oxidase activity. In this study, we e...

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Bibliografske podrobnosti
izdano v:J Am Heart Assoc
Main Authors: Yang, Yajuan, Zhao, Jianping, Qiu, Jiuchun, Li, Jian, Liang, Xue, Zhang, Zhiwei, Zhang, Xiaowei, Fu, Huaying, Korantzopoulos, Panagiotis, Letsas, Konstantinos P., Tse, Gary, Li, Guangping, Liu, Tong
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6015332/
https://ncbi.nlm.nih.gov/pubmed/29720500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.118.008807
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