Xanthine Oxidase Inhibitor Allopurinol Prevents Oxidative Stress‐Mediated Atrial Remodeling in Alloxan‐Induced Diabetes Mellitus Rabbits

BACKGROUND: There are several mechanisms, including inflammation, oxidative stress and abnormal calcium homeostasis, involved in the pathogenesis of atrial fibrillation. In diabetes mellitus (DM), increased oxidative stress may be attributable to higher xanthine oxidase activity. In this study, we e...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Yang, Yajuan, Zhao, Jianping, Qiu, Jiuchun, Li, Jian, Liang, Xue, Zhang, Zhiwei, Zhang, Xiaowei, Fu, Huaying, Korantzopoulos, Panagiotis, Letsas, Konstantinos P., Tse, Gary, Li, Guangping, Liu, Tong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6015332/
https://ncbi.nlm.nih.gov/pubmed/29720500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.118.008807
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