Xanthine Oxidase Inhibitor Allopurinol Prevents Oxidative Stress‐Mediated Atrial Remodeling in Alloxan‐Induced Diabetes Mellitus Rabbits

BACKGROUND: There are several mechanisms, including inflammation, oxidative stress and abnormal calcium homeostasis, involved in the pathogenesis of atrial fibrillation. In diabetes mellitus (DM), increased oxidative stress may be attributable to higher xanthine oxidase activity. In this study, we e...

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Bibliografski detalji
Izdano u:J Am Heart Assoc
Glavni autori: Yang, Yajuan, Zhao, Jianping, Qiu, Jiuchun, Li, Jian, Liang, Xue, Zhang, Zhiwei, Zhang, Xiaowei, Fu, Huaying, Korantzopoulos, Panagiotis, Letsas, Konstantinos P., Tse, Gary, Li, Guangping, Liu, Tong
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2018
Teme:
Original Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6015332/
https://ncbi.nlm.nih.gov/pubmed/29720500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.118.008807
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