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Loss of the Liver X Receptors Disrupts the Balance of Hematopoietic Populations, With Detrimental Effects on Endothelial Progenitor Cells

BACKGROUND: The liver X receptors (LXRs; α/β) are nuclear receptors known to regulate cholesterol homeostasis and the production of select hematopoietic populations. The objective of this study was to determine the importance of LXRs and a high‐fat high‐cholesterol diet on global hematopoiesis, with...

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Veröffentlicht in:J Am Heart Assoc
Hauptverfasser: Rasheed, Adil, Tsai, Ricky, Cummins, Carolyn L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6015321/
https://ncbi.nlm.nih.gov/pubmed/29739800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.117.007787
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