On the Evolutionary Conservation of the Cell Death Pathway: Mitochondrial Release of an Apoptosis-inducing Factor during Dictyostelium discoideum Cell Death

Mitochondria play a pivotal role in apoptosis in multicellular organisms by releasing apoptogenic factors such as cytochrome c that activate the caspases effector pathway, and apoptosis-inducing factor (AIF) that is involved in a caspase-independent cell death pathway. Here we report that cell death...

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Main Authors: Arnoult, Damien, Tatischeff, Irène, Estaquier, Jérome, Girard, Mathilde, Sureau, Franck, Tissier, Jean Pierre, Grodet, Alain, Dellinger, Marc, Traincard, François, Kahn, Axel, Ameisen, Jean-Claude, Petit, Patrice Xavier
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2001
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC60152/
https://ncbi.nlm.nih.gov/pubmed/11598188
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