Interleukin 7 Increases Human Immunodeficiency Virus Type 1 LAI-Mediated Fas-Induced T-Cell Death

Fas-mediated T-cell death is known to occur during human immunodeficiency virus (HIV) infection. In this study, we found that HIV type 1 LAI (HIV-1(LAI)) primes CD8(+) T cells from healthy donors for apoptosis, which occurs after Fas ligation. This effect is counteracted by a broad caspase inhibitor...

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Detalhes bibliográficos
Main Authors: Lelièvre, Jean-Daniel, Petit, Frédéric, Arnoult, Damien, Ameisen, Jean-Claude, Estaquier, Jérôme
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC548424/
https://ncbi.nlm.nih.gov/pubmed/15709041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.5.3195-3199.2005
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