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Comparative Analysis of Mutant Huntingtin Binding Partners in Yeast Species
Huntington’s disease is caused by the pathological expansion of a polyglutamine (polyQ) stretch in Huntingtin (Htt), but the molecular mechanisms by which polyQ expansion in Htt causes toxicity in selective neuronal populations remain poorly understood. Interestingly, heterologous expression of expa...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6015068/ https://ncbi.nlm.nih.gov/pubmed/29934597 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27900-5 |
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