Cysteine allows ovarian cancer cells to adapt to hypoxia and to escape from carboplatin cytotoxicity

Ovarian cancer is the second most common gynaecologic malignancy and the main cause of death from gynaecologic cancer, due to late diagnosis and chemoresistance. Studies have reported the role of cysteine in cancer, by contributing for hydrogen sulphide (H(2)S) generation and as a precursor of gluta...

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Pubblicato in:Sci Rep
Autori principali: Nunes, Sofia C., Ramos, Cristiano, Lopes-Coelho, Filipa, Sequeira, Catarina O., Silva, Fernanda, Gouveia-Fernandes, Sofia, Rodrigues, Armanda, Guimarães, António, Silveira, Margarida, Abreu, Sofia, Santo, Vítor E., Brito, Catarina, Félix, Ana, Pereira, Sofia A., Serpa, Jacinta
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6015047/
https://ncbi.nlm.nih.gov/pubmed/29934500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27753-y
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