Cysteine allows ovarian cancer cells to adapt to hypoxia and to escape from carboplatin cytotoxicity

Ovarian cancer is the second most common gynaecologic malignancy and the main cause of death from gynaecologic cancer, due to late diagnosis and chemoresistance. Studies have reported the role of cysteine in cancer, by contributing for hydrogen sulphide (H(2)S) generation and as a precursor of gluta...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Nunes, Sofia C., Ramos, Cristiano, Lopes-Coelho, Filipa, Sequeira, Catarina O., Silva, Fernanda, Gouveia-Fernandes, Sofia, Rodrigues, Armanda, Guimarães, António, Silveira, Margarida, Abreu, Sofia, Santo, Vítor E., Brito, Catarina, Félix, Ana, Pereira, Sofia A., Serpa, Jacinta
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6015047/
https://ncbi.nlm.nih.gov/pubmed/29934500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27753-y
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