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The E3 ubiquitin ligase SMURF1 regulates cell-fate specification and outflow tract septation during mammalian heart development
Smad ubiquitin regulatory factor 1 (SMURF1) is a HECT-type E3 ubiquitin ligase that plays a critical role in vertebrate development by regulating planar cell polarity (PCP) signaling and convergent extension (CE). Here we show that SMURF1 is involved in mammalian heart development. We find that SMUR...
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Vydáno v: | Sci Rep |
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Hlavní autoři: | , , , , , , , , , , , , , , , |
Médium: | Artigo |
Jazyk: | Inglês |
Vydáno: |
Nature Publishing Group UK
2018
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Témata: | |
On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6015040/ https://ncbi.nlm.nih.gov/pubmed/29934521 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27854-8 |
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