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Distinct submembrane localisation compartmentalises cardiac NPR1 and NPR2 signalling to cGMP

Natriuretic peptides (NPs) are important hormones that regulate multiple cellular functions including cardiovascular physiology. In the heart, two natriuretic peptide receptors NPR1 and NPR2 act as membrane guanylyl cyclases to produce 3′,5′-cyclic guanosine monophosphate (cGMP). Although both recep...

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書目詳細資料
發表在:Nat Commun
Main Authors: Subramanian, Hariharan, Froese, Alexander, Jönsson, Peter, Schmidt, Hannes, Gorelik, Julia, Nikolaev, Viacheslav O.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6014982/
https://ncbi.nlm.nih.gov/pubmed/29934640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04891-5
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