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Second-Generation DNA-Templated Macrocycle Libraries for the Discovery of Bioactive Small Molecules
DNA-encoded libraries have emerged as a widely used resource for discovery of bioactive small molecules and offer substantial advantages compared to conventional small-molecule libraries. Here we developed and streamlined multiple fundamental aspects of DNA-encoded and DNA-templated library synthesi...
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| Publicado no: | Nat Chem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6014893/ https://ncbi.nlm.nih.gov/pubmed/29610462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41557-018-0033-8 |
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