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Lipid Rafts Act as Specialized Domains for Tetanus Toxin Binding and Internalization into Neurons

Tetanus (TeNT) is a zinc protease that blocks neurotransmission by cleaving the synaptic protein vesicle-associated membrane protein/synaptobrevin. Although its intracellular catalytic activity is well established, the mechanism by which this neurotoxin interacts with the neuronal surface is not kno...

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Bibliografiske detaljer
Main Authors: Herreros, Judit, Ng, Tony, Schiavo, Giampietro
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC60147/
https://ncbi.nlm.nih.gov/pubmed/11598183
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