T(3) Induces Both Markers of Maturation and Aging in Pancreatic β-Cells

Previously, we showed that thyroid hormone (TH) triiodothyronine (T(3)) enhanced β-cell functional maturation through induction of Mafa. High levels of T(3) have been linked to decreased life span in mammals and low levels to lengthened life span, suggesting a relationship between TH and aging. Here...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Diabetes
Autori principali: Aguayo-Mazzucato, Cristina, Lee, Terence B., Matzko, Michelle, DiIenno, Amanda, Rezanejad, Habib, Ramadoss, Preeti, Scanlan, Thomas, Zavacki, Ann Marie, Larsen, P. Reed, Hollenberg, Anthony, Colton, Clark, Sharma, Arun, Bonner-Weir, Susan
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Diabetes Association 2018
Soggetti:
Islet Studies
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6014556/
https://ncbi.nlm.nih.gov/pubmed/29625991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db18-0030
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