Spindle assembly checkpoint strength is linked to cell fate in the Caenorhabditis elegans embryo

The spindle assembly checkpoint (SAC) is a conserved mitotic regulator that preserves genome stability by monitoring kinetochore–microtubule attachments and blocking anaphase onset until chromosome biorientation is achieved. Despite its central role in maintaining mitotic fidelity, the ability of th...

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Bibliographic Details
Published in:Mol Biol Cell
Main Authors: Gerhold, Abigail R., Poupart, Vincent, Labbé, Jean-Claude, Maddox, Paul S.
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6014101/
https://ncbi.nlm.nih.gov/pubmed/29688794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E18-04-0215
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