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Spindle assembly checkpoint strength is linked to cell fate in the Caenorhabditis elegans embryo

The spindle assembly checkpoint (SAC) is a conserved mitotic regulator that preserves genome stability by monitoring kinetochore–microtubule attachments and blocking anaphase onset until chromosome biorientation is achieved. Despite its central role in maintaining mitotic fidelity, the ability of th...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Gerhold, Abigail R., Poupart, Vincent, Labbé, Jean-Claude, Maddox, Paul S.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6014101/
https://ncbi.nlm.nih.gov/pubmed/29688794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E18-04-0215
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