Genetic restriction of antigen-presentation dictates allergic sensitization and disease in humanized mice

BACKGROUND: Immunoglobulin(Ig)E-associated allergies result from misguided immune responses against innocuous antigens. CD4(+) T lymphocytes are critical for initiating and perpetuating that process, yet the crucial factors determining whether an individual becomes sensitized towards a given allerge...

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Publicat a:EBioMedicine
Autors principals: Neunkirchner, Alina, Kratzer, Bernhard, Köhler, Cordula, Smole, Ursula, Mager, Lukas F., Schmetterer, Klaus G., Trapin, Doris, Leb-Reichl, Victoria, Rosloniec, Edward, Naumann, Ronald, Kenner, Lukas, Jahn-Schmid, Beatrice, Bohle, Barbara, Valenta, Rudolf, Pickl, Winfried F.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2018
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6014064/
https://ncbi.nlm.nih.gov/pubmed/29678672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.04.001
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