Active enhancer and chromatin accessibility landscapes chart the regulatory network of primary multiple myeloma

Multiple myeloma (MM) is an aggressive cancer that originates from antibody-secreting plasma cells. Although genetically and transcriptionally well characterized, the aberrant gene regulatory networks that underpin this disease remain poorly understood. Here, we mapped regulatory elements, open chro...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Blood
Prif Awduron: Jin, Yi, Chen, Kenian, De Paepe, Ayla, Hellqvist, Eva, Krstic, Aleksandra D., Metang, Lauren, Gustafsson, Charlotte, Davis, Richard E., Levy, Yair M., Surapaneni, Rakesh, Wallblom, Ann, Nahi, Hareth, Mansson, Robert, Lin, Yin C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Hematology 2018
Pynciau:
Lymphoid Neoplasia
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6014038/
https://ncbi.nlm.nih.gov/pubmed/29519805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-09-808063
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