Active enhancer and chromatin accessibility landscapes chart the regulatory network of primary multiple myeloma

Multiple myeloma (MM) is an aggressive cancer that originates from antibody-secreting plasma cells. Although genetically and transcriptionally well characterized, the aberrant gene regulatory networks that underpin this disease remain poorly understood. Here, we mapped regulatory elements, open chro...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Jin, Yi, Chen, Kenian, De Paepe, Ayla, Hellqvist, Eva, Krstic, Aleksandra D., Metang, Lauren, Gustafsson, Charlotte, Davis, Richard E., Levy, Yair M., Surapaneni, Rakesh, Wallblom, Ann, Nahi, Hareth, Mansson, Robert, Lin, Yin C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2018
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6014038/
https://ncbi.nlm.nih.gov/pubmed/29519805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-09-808063
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