Characterization of Chlamydial Rho and the Role of Rho-Mediated Transcriptional Polarity during Interferon Gamma-Mediated Tryptophan Limitation

As an obligate intracellular, developmentally regulated bacterium, Chlamydia is sensitive to amino acid fluctuations within its host cell. When human epithelial cells are treated with the cytokine interferon gamma (IFN-γ), the tryptophan (Trp)-degrading enzyme, indoleamine-2,3-dioxygenase, is induce...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Ouellette, Scot P., Messerli, Parker R., Wood, Nicholas A., Hajovsky, Heather
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6013675/
https://ncbi.nlm.nih.gov/pubmed/29712731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00240-18
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