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Tryptophan Prototrophy Contributes to Francisella tularensis Evasion of Gamma Interferon-Mediated Host Defense

Francisella tularensis is able to survive and replicate within host macrophages, a trait that is associated with the high virulence of this bacterium. The trpAB genes encode the enzymes required for the final two steps in tryptophan biosynthesis, with TrpB being responsible for the conversion of ind...

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Detalhes bibliográficos
Main Authors: Chu, Ping, Rodriguez, Annette R., Arulanandam, Bernard P., Klose, Karl E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3125836/
https://ncbi.nlm.nih.gov/pubmed/21464086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01349-10
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