A Capsular Polysaccharide-Specific Antibody Alters Streptococcus pneumoniae Gene Expression during Nasopharyngeal Colonization of Mice

Pneumococcal conjugate vaccines (PCV) elicit opsonophagocytic (opsonic) antibodies to pneumococcal capsular polysaccharides (PPS) and reduce nasopharyngeal (NP) colonization by vaccine-included Streptococcus pneumoniae serotypes. However, nonopsonic antibodies may also be important for protection ag...

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Publicado en:Infect Immun
Autores principales: Doyle, Christopher R., Moon, Jee-Young, Daily, Johanna P., Wang, Tao, Pirofski, Liise-anne
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2018
Materias:
Microbial Immunity and Vaccines
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6013671/
https://ncbi.nlm.nih.gov/pubmed/29735523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00300-18
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