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Entamoeba histolytica Alters Ileal Paneth Cell Functions in Intact and Muc2 Mucin Deficiency

Enteric α-defensins, termed cryptdins (Crps) in mice, and lysozymes secreted by Paneth cells contribute to innate host defense in the ileum. Antimicrobial factors, including lysozymes and β-defensins, are often embedded in luminal glycosylated colonic Muc2 mucin secreted by goblet cells that form th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Cobo, Eduardo R., Holani, Ravi, Moreau, France, Nakamura, Kiminori, Ayabe, Tokiyoshi, Mastroianni, Jennifer R., Eriguchi, Yoshihiro, Ouellette, Andre, Chadee, Kris
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6013658/
https://ncbi.nlm.nih.gov/pubmed/29685982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00208-18
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