Anti-apoptotic protein BIRC5 maintains survival of HIV-1-infected CD4(+) T cells

HIV-1 infection of CD4(+) T cells leads to cytopathic effects and cell demise, which is counter to the observation that certain HIV-1-infected cells possess a remarkable long-term stability and can persist lifelong in infected individuals treated with suppressive antiretroviral therapy (ART). Using...

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Publicat a:Immunity
Autors principals: Kuo, Hsiao-Hsuan, Ahmad, Rushdy, Lee, Guinevere Q., Gao, Ce, Chen, Hsiao-Rong, Ouyang, Zhengyu, Szucs, Matthew J., Kim, Dhohyung, Tsibris, Athe, Chun, Tae-Wook, Battivelli, Emilie, Verdin, Eric, Rosenberg, Eric S., Carr, Steven A., Yu, Xu G., Lichterfeld, Mathias
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6013384/
https://ncbi.nlm.nih.gov/pubmed/29802019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2018.04.004
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