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Melanoma cases demonstrate increased carrier frequency of Phenylketonuria/hyperphenylalanemia mutations

Identifying novel melanoma genetic risk factors informs screening and prevention efforts. Mutations in the phenylalanine hydroxylase gene (the causative gene in phenylketonuria) lead to reduced pigmentation in untreated phenylketonuria patients, and reduced pigmentation is associated with greater me...

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Detalhes bibliográficos
Publicado no:Pigment Cell Melanoma Res
Main Authors: Arbesman, Joshua, Ravichandran, Sairekha, Funchain, Pauline, Thompson, Cheryl L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6013363/
https://ncbi.nlm.nih.gov/pubmed/29473999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pcmr.12695
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