LRP-1 Attenuates House Dust Mite-induced Eosinophilic Airway Inflammation by Suppressing Dendritic Cell-mediated Adaptive Immune Responses

BACKGROUND: The LDL-receptor related protein 1 (LRP-1) is a scavenger receptor that regulates adaptive immunity and inflammation. LRP-1 is not known to modulate the pathogenesis of allergic asthma. OBJECTIVE: To assess whether LRP-1 expression by dendritic cells (DCs) modulates adaptive immune respo...

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Publicado no:J Allergy Clin Immunol
Main Authors: Mishra, Amarjit, Yao, Xianglan, Saxena, Ankit, Gordon, Elizabeth M., Kaler, Maryann, Cuento, Rosemarie A., Barochia, Amisha V., Dagur, Pradeep K., McCoy, J. Philip, Keeran, Karen J., Jeffries, Kenneth R., Qu, Xuan, Yu, Zu-Xi, Levine, Stewart J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6013321/
https://ncbi.nlm.nih.gov/pubmed/29274414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2017.10.044
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