A CCL24-dependent Pathway Augments Eosinophilic Airway Inflammation in House Dust Mite-challenged Cd163(−/−) Mice

CD163 is a macrophage scavenger receptor with anti-inflammatory and pro-inflammatory functions. Here, we report that alveolar macrophages (AMΦs) from asthmatic subjects had reduced cell surface expression of CD163, which suggested that CD163 might modulate the pathogenesis of asthma. Consistent with...

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Bibliografiska uppgifter
I publikationen:Mucosal Immunol
Huvudupphovsmän: Dai, Cuilian, Yao, Xianglan, Gordon, Elizabeth M., Barochia, Amisha, Cuento, Rosemarie A., Kaler, Maryann, Meyer, Katharine S., Keeran, Karen J., Nugent, Gayle Z., Jeffries, Kenneth R., Qu, Xuan, Yu, Zu-Xi, Aponte, Angel, Gucek, Marjan, Dagur, Pradeep K., McCoy, J. Philip, Levine, Stewart J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794428/
https://ncbi.nlm.nih.gov/pubmed/26376364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2015.94
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