A CCL24-dependent Pathway Augments Eosinophilic Airway Inflammation in House Dust Mite-challenged Cd163(−/−) Mice

CD163 is a macrophage scavenger receptor with anti-inflammatory and pro-inflammatory functions. Here, we report that alveolar macrophages (AMΦs) from asthmatic subjects had reduced cell surface expression of CD163, which suggested that CD163 might modulate the pathogenesis of asthma. Consistent with...

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Udgivet i:Mucosal Immunol
Main Authors: Dai, Cuilian, Yao, Xianglan, Gordon, Elizabeth M., Barochia, Amisha, Cuento, Rosemarie A., Kaler, Maryann, Meyer, Katharine S., Keeran, Karen J., Nugent, Gayle Z., Jeffries, Kenneth R., Qu, Xuan, Yu, Zu-Xi, Aponte, Angel, Gucek, Marjan, Dagur, Pradeep K., McCoy, J. Philip, Levine, Stewart J.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794428/
https://ncbi.nlm.nih.gov/pubmed/26376364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2015.94
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