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The Multifunctional Protein BAG3: A Novel Therapeutic Target in Cardiovascular Disease
The B-cell lymphoma 2–associated anthanogene (BAG3) protein is expressed most prominently in the heart, the skeletal muscle, and in many forms of cancer. In the heart, it serves as a co-chaperone with heat shock proteins in facilitating autophagy; binds to B-cell lymphoma 2, resulting in inhibition...
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| Publicado no: | JACC Basic Transl Sci |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6013050/ https://ncbi.nlm.nih.gov/pubmed/29938246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2017.09.009 |
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