The Multifunctional Protein BAG3: A Novel Therapeutic Target in Cardiovascular Disease

The B-cell lymphoma 2–associated anthanogene (BAG3) protein is expressed most prominently in the heart, the skeletal muscle, and in many forms of cancer. In the heart, it serves as a co-chaperone with heat shock proteins in facilitating autophagy; binds to B-cell lymphoma 2, resulting in inhibition...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:JACC Basic Transl Sci
Main Authors: Myers, Valerie D., McClung, Joseph M., Wang, JuFang, Tahrir, Farzaneh G., Gupta, Manish K., Gordon, Jennifer, Kontos, Christopher H., Khalili, Kamel, Cheung, Joseph Y., Feldman, Arthur M.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2018
Teme:
STATE-OF-THE-ART REVIEW
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6013050/
https://ncbi.nlm.nih.gov/pubmed/29938246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2017.09.009
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