DIPG-54. TREATMENT OF A PEDIATRIC PATIENT WITH AN H3.3 K27M MUTANT DIPG WITH ONC201, A SELECTIVE DRD2 ANTAGONIST

Although radiotherapy is the mainstay of treatment for children with diffuse intrinsic pontine gliomas (DIPG), fewer than 10% of patients survive past two years from diagnosis despite 30 years of clinical trials. ONC201 is an oral, selective DRD2 antagonist that induces p53-independent apoptosis and...

詳細記述

保存先:
書誌詳細
出版年:Neuro Oncol
主要な著者: Suarez, Fernando, Stafford, James M, Tarapore, Rohinton, Oster, Wolfgang, Allen, Joshua E, Chi, Andrew S, Gardner, Sharon
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2018
主題:
Abstracts
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012976/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.147
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