IMMU-15. HIGH-RESOLUTION ANALYSIS OF THE T-CELL RECEPTOR REPERTOIRE AFTER ADOPTIVE CELLULAR THERAPY IN PEDIATRIC PATIENTS WITH CENTRAL PNETs (Re-MATCH TRIAL)

Adoptive cellular therapy (ACT) using transfer of tumor-specific lymphocytes has emerged as a potent strategy for treatment of advanced and refractory malignancies. We have employed deep TCR repertoire sequencing approach to explore dynamics of T-cell immunity in the nine patients with recurrent med...

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Pubblicato in:Neuro Oncol
Autori principali: Yegorov, Oleg, Yegorova, Yanina, Dechkovskaia, Anjelika, Gururangan, Sridharan, Mitchell, Duane
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012895/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.331
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