HGG-45. COMPREHENSIVE MOLECULAR CHARACTERIZATION OF PEDIATRIC TREATMENT-INDUCED HIGH-GRADE GLIOMA: GERMLINE DNA REPAIR DEFECTS AS A POTENTIAL ETIOLOGY

BACKGROUND: Pediatric treatment-induced high-grade glioma (TIHGG) is an incurable late complication of cranial radiation therapy or combined radiation/chemotherapy. Previously, we showed TIHGG gene expression differs from spontaneous pediatric HGG and defined two TIHGG groups (A & B) by transcri...

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Publicat a:Neuro Oncol
Autors principals: DeSisto, John, Lucas, John, Donson, Andrew, Sanford, Bridget, Wu, Gang, Armstrong, Gregory, Arnold, Michael, Bhatia, Smita, Flannery, Patrick, Lemma, Rakeb, Hardie, Lakotah, Hoffman, Lindsey, Dorris, Kathleen, Liu, Arthur, Foreman, Nicholas, Vibhakar, Rajeev, Jones, Kenneth, Allen, Sariah, Baker, Suzanne, Merchant, Thomas, Orr, Brent, Green, Adam
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
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Abstracts
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012867/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.316
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