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IMMU-24. IMMUNOTHERAPEUTIC NANOTECHNOLOGY TARGETING IDO1 FOR PEDIATRIC DIFFUSE INTRINSIC PONTINE GLIOMA

BACKGROUND: Research on adult high-grade gliomas has shown a targetable pathway through the inflammation-induced expression of indoleamine 2,3 dioxygenase (IDO1) and its recognized ability to suppress the anti-tumor immune response. Our project delineates the role of indoleamine 2,3 dioxygenase 1 (I...

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Publicat a:Neuro Oncol
Autors principals: Lenzen, Alicia, Cole, Lisa, Lauing, Kristen L, Zhai, Lijie, Ladomersky, Erik, Lulla, Rishi R, Hashizume, Rintaro, Stegh, Alexander, Wainwright, Derek A
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012849/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.340
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