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DIPG-21. EVALUATING THERAPEUTIC VULNERABILITIES IN DIPG USING AURORA KINASE INHIBITOR AS A NOVEL THERAPY
DIPG is one of the most aggressive pediatric brain tumors with no effective therapies. Majority of the midline high-grade pediatric gliomas carry somatic mutations of histone H3 resulting in the replacement of lysine 27 by methionine (K27M) and global loss of trimethylation on H3K27. In an effort to...
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| Publicado no: | Neuro Oncol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6012767/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.114 |
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