PCLN-06. NOVEL TUMOR-DERIVED MODELS OF CNS HGNET-BCOR PROVIDE INSIGHTS INTO UNDERLYING MOLECULAR MECHANISMS AND INNOVATIVE THERAPEUTIC OPTIONS

Central nervous system high-grade neuroepithelial tumor with BCL6-corepressor alteration (CNS HGNET-BCOR) is a recently discovered molecular brain tumor entity characterized by genomic alterations of BCOR, a central component of a non-canonical polycomb repressive complex. However, the underlying on...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Gojo, Johannes, Kirchhofer, Dominik, Lötsch, Daniela, Mohr, Thomas, Pirker, Christine, Pajtler, Kristian W, Okonechnikov, Konstantin, Englinger, Bernhard, Boidol, Bernd, Lardeau, Charles-Hugues, Czech, Thomas, Kubicek, Stefan, Sturm, Dominik, Pfister, Stefan M, Peyrl, Andreas, Haberler, Christine, Kool, Marcel, Berger, Walter, Slavc, Irene
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
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Abstracts
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012741/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.575
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