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DR-01 NOVEL PEDIATRIC EPENDYMOMA MODELS SHOW HIGH CHEMOTHERAPY-RESISTANCE AND HYPERACTIVATION OF ABC-TRANSPORTERS

Malignant ependymoma is one of the most frequent CNS-tumors in childhood characterized by a poor outcome owing to low effects of chemotherapy accompanied by high rates of recurrence. However, the underlying mechanisms are still poorly understood. Aim of this study is to investigate the role of ABC-t...

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Autori principali: Gojo, Johannes, Lötsch, Daniela, Pirker, Christine, Araki, Asuka, Peyrl, Andreas, Chocholous, Monika, Stefanits, Harald, Czech, Thomas, Haberler, Christine, Slavc, Irene, Berger, Walter
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218040/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou252.1
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