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ATRT-37. TARGETING ATYPICAL TERATOID/RHABDOID TUMOR USING MATURE LET-7 LEADS TO INCREASED APOPTOSIS
Atypical teratoid rhabdoid tumors (AT/RT) are one of the most malignant brain tumors of childhood with very limited treatment options available. AT/RT tumors are characterized by INI1 (SMARCB1/BAF47/SNF5) loss. Deletions or mutations in INI1 is associated with upregulation of LIN28 which is a regula...
Gardado en:
| Publicado en: | Neuro Oncol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6012652/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.034 |
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