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MEK Inhibition Suppresses Growth of Atypical Teratoid/Rhabdoid Tumors

Atypical teratoid/rhabdoid (AT/RT) tumors are the most common malignant brain tumor of infancy and have a poor prognosis. We have previously identified very high expression of LIN28A and/or LIN28B in AT/RT tumors and showed that AT/RT have corresponding increased expression of the mitogen-activated...

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Bibliografiske detaljer
Udgivet i:J Neuropathol Exp Neurol
Main Authors: Shahab, Shubin, Rubens, Jeffrey, Kaur, Harpreet, Sweeney, Heather, Eberhart, Charles G, Raabe, Eric H
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7821707/
https://ncbi.nlm.nih.gov/pubmed/32472116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnen/nlaa042
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