TBIO-09. IN VITRO EVALUATION OF THE POTENTIAL OF GLUCOSE RESTRICTION AS AN ADJUVANT THERAPY FOR PAEDIATRIC BRAIN TUMOURS

Brain tumours are the most challenging cancers in relation to diagnosis, treatment and outcome. Under normal physiological conditions, brain cells metabolise glucose for energy. If glucose deprived they instead metabolise ketone bodies (KBs). Mitochondrial defects in brain tumours obviate this metab...

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Gepubliceerd in:Neuro Oncol
Hoofdauteurs: Lockwood, George, Apte, Janhavi, Ivanov, Delyan, Parr, Rebecca, Walker, David A, Storer, Lisa CD, Grundy, Richard G
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012642/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.698
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