IMMU-05. SAFETY AND EFFICACY OF INTRAVENTRICULAR (131)I-LABELED MONOCLONAL ANTIBODY 8H9 TARGETING THE SURFACE GLYCOPROTEIN B7-H3

BACKGROUND: Tumors metastasizing to the CNS are associated with significant mortality. We tested the toxicity and dosimetry of intraventricular (131)I-labeled monoclonal antibody 8H9 targeting B7-H3 in patients with CNS tumors. METHODS: Tumor B7-H3 expression was assessed by immunohistochemistry. Pa...

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Vydáno v:Neuro Oncol
Hlavní autoři: Kramer, Kim, Kushner, Brian, Modak, Shakeel, Taskar, Neeta Pandit, Tomlinson, Ursula, Donzelli, Maria, Wolden, Suzanne, Zanzonico, Pat, Humm, John, Haque, Sofia, Souweidane, Mark, Greenfield, Jeffrey, Basu, Ellen, Roberts, Stephen, Carrasquillo, Jorge, Lewis, Jason, Lyashchenko, Serge, Larson, Steven, Cheung, Nai-Kong
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012628/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.321
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