DIPG-20. PRE-RANDOMISATION CENTRAL REVIEW AND REAL-TIME BIOMARKERS SCREENING IN THE MULTICENTRE BIOLOGICAL MEDICINE FOR DIPG ERADICATION (BIOMEDE) TRIAL: LESSONS LEARNT FROM THE FIRST 120 BIOPSIES

INTRODUCTION: BIOMEDE is a multicentre, phase-II trial comparing efficacy of erlotinib, everolimus, and dasatinib in combination with radiotherapy, in newly diagnosed diffuse intrinsic pontine glioma (DIPG) (NCT02233049). Randomisation is based on biomarkers determined in upfront stereotactic biopsi...

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Vydáno v:Neuro Oncol
Hlavní autoři: Varlet, Pascale, Debily, Marie-Anne, Teuff, Gwenael Le, Tauziede-Espariat, Arnault, Pages, Mélanie, Andreiuolo, Felipe, Lechapt-Zalcman, Emanuele, Barret, Emilie, Picot, Stephanie, Nysom, Karsten, Pravong, Sophie, Vassal, Gilles, Castel, David, Puget, Stephanie, Grill, Jacques
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012153/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.113
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