MBRS-62. REPRESSIVE CHROMATIN REMODELERS IN SHH-DRIVEN MEDULLOBLASTOMA

Medulloblastoma (MB) is a malignant pediatric brain tumor characterized by poor neuronal differentiation. The RE1 Silencing Transcription Factor (REST), which negatively regulates neurogenesis by promoting repressive chromatin remodeling via epigenetic modifications, is overexpressed in human MBs. A...

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Publicado no:Neuro Oncol
Main Authors: Tao, Rong-Hua, Dobson, Tara, Maegawa, Shinji, Swaminathan, Jyothismathi, Shaik, Shavali, Taylor, Pete, Kennis, Bridget, Qi, Lin, Khatua, Soumen, Goldman, Stewart, Lulla, Rishi, Fangusaro, Jason, MacDonald, Tobey, Li, Xiao-Nan, Hawkins, Cynthia, Rajaram, Veena, Gopalakrishnan, Vidya
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012124/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.506
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